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2017年11月19日 星期日  
 
 
张大同

 
姓 名
 张大同
性 别
 男
出生年月
 1973.04
学 历
 研究生
毕业时间
 2006.06
专 业
 药物化学、有机化学
电 话
13708925788
邮 编
 250353
E-Mail
 datong_zhang@163.com
单 位
 化学与制药工程学院
通信地址
 
济南市长清区大学路3501号 齐鲁工业大学化工学院
个人简历:

1991.9-1995.7,山东医科大学 药学专业 本科;
1995.9-1998.7,山东医科大学 药物化学专业 硕士;
2003.09-2006.7,山东大学 有机化学专业 博士;
2006.7至今,山东轻工业学院化学工程学院任教。化工制药系教授,硕士研究生导师
2012.7-2013.1,美国Virginia Commonwealth University 访问学者

研究方向:
药物化学、有机荧光探针。
奖励和荣誉:

2007年指导的论文被评为“校级优秀本科毕业论文”.
2008年指导的论文被评为“校级优秀本科毕业论文”.
2009年指导的论文被评为“校级优秀本科毕业论文”.
2012年指导的论文被评为“校级优秀本科毕业论文”.

2008年指导的论文被评为2009年“山东省优秀学士学位论文”.

2011年被评为山东轻工业学院优秀教师.

发表文章:
1. Xiao-Bo Wang, Xue Hao, Datong  Zhang*,  Yan Jiang. Reaction-based Fluorescent Turn-on Probe for Selective Detection of Thiophenols in Aqueous Solution and Living Cell. Dyes and Pigments, 2017, 142, 167-174 .
2. Xiao-Bo Wang, Datong  Zhang*. A novel reaction-based fluorescent turn-on probe for biothiols and its application in cell imaging. Sensors and Actuators B, 241 (2017) 327–334.
3. Xiao-Bo Wang, Jianhua Zhou, Datong  Zhang and Bin Wang. A very fast 3-hydroxy-coumarin-based fluorescent probe for highly selective and sensitive detection of thiophenols and its application in water samples. Anal. Methods, 2016, 8, 6916–6922.
4. Ruibing An, Peng Wei, Datong  Zhang*, na Su , A highly selective 7-hydroxy-3-methyl-benzoxazinone based fluorescent probe for instant detection of thiophenols in environmental samples. Tetrahedron Letters, 2016, 57, 3039-3042.
5. Ruibing  An,  Datong  Zhang,*,  Yan  Chen,  Yue-zhi  Cui. A “turn-on” fluorescent and colorimetric sensor   for selective 
detection of Cu2+ in aqueous  media  and  living  cells. Sensors and Actuators B, 222 (2016) 48–54.
6. Peng Wei, Datong Zhang*, Zhigang Gao, Wenqing Cai, Weiren Xu, Lida Tang and Guilong Zhao*. Iodine Monochloride  (ICl) as a Highly Efficient, Green Oxidant for the Oxidation of Alcohols to Corresponding Carbonyl Compounds.  Synthetic  Communications
,  2015, 45(12):1457-1470.
7.
Datong Zhang*, Yuntong Ma, Ruibing An. New colorimetric chemosensor based on rhodamine hydrazide to detect Cu2+ ions by naked eye. Res Chem Intermed., 2015, 41(8): 5059-5069.
8.
Gao Zhigang, Zhang Datong*, Wei Peng, Wang Zhe, Xie Yafei, Liu Yuqiang, Xu Weiren, Tang Lida, Zhao Guilong*. A facile convergent synthetic procedure for 3-deoxydapagliflozin as SGLT2 inhibitor. Chin. J. Org. Chem, 2014, 34, 1829-1939..
9.
Datong Zhang, Yuntong Ma, Yu Liu and Zhao-Peng Liu. Synthesis of sulfonylhydrazone- and acylhydrazone- substituted  8-ethoxy-3-nitro-2H-chromenes as potent antiproliferative and apoptosis inducing agents. Arch. Pharm. Life Sci. 2014, 347, 576-588.

10
. Datong Zhang*, Lingyan Huo, Laichun Lu, Qiong Yu, Jianwu Wang, Yanyan Yang. Synthesis and preliminary antibacterial evaluation of hydroxamic acid and N-formyl hydroxylamine derivatives bearing oxazole ring. Medicinal Chemistry Research, 2013, 22(3):1426-1437.
11.
Datong Zhang*, Guangtian Wang, Guilong Zhao,Weiren Xu, Lingyan Huo. Synthesis and Cytotoxic Activity of Novel  3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives . European Journal of Medicinal Chemistry, 2011,46 (12):5868-5877.
12.
Datong Zhang*, Guangtian Wang, Chubing Tan*,  Weiren Xu, Yuan Pei and Lingyan Huo. Synthesis and biological evaluation of 3-(1H-indol-3-yl)pyrazole-5-carboxylic acid derivatives. Archives of Pharmacal research, 2011, 34(3):343-355.  
13.Datong Zhang*, Jiong Jia, Lijuan Meng, Weiren Xu, Lida Tang, and Jianwu Wang. Synthesis and Preliminary Antibacterial Evaluation of 2-Butyl Succinate-based Hydroxamate Derivatives Containing Isoxazole Rings. Archives of Pharmacal research, 2010, 33(6):831-842.
14. Datong Zhang, Zongheng Wang, Weiren Xu, Fanggang Sun, and Jianwu Wang. Design,Synthesis and Antibacterial Activity of Novel Actinonin Derivatives Containing Benzimidazole Heterocycles. European Journal of Medicinal Chemistry, 2009,44 (5),2202-2210 
 
目前承担和参与项目:
先后主持和参与了山东省自然科学基金、山东省中青年科学家奖励基金和济南市高校院所自主创新计划, 并承担多项企事业单位横向课题。
社会兼职:

中国化学会会员。现为Bioorganic & medicinal chemistry letter、European journal of medicinal chemistry、Journal of heterocyclic chemistry、Medicinal Chemistry Research等期刊审稿专家。

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